Collagenase activity in sulcal fluid of patients with localized juvenile periodontitis
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Collagenase activity in sulcal fluid of patients with localized juvenile periodontitis by Jacinthe Larivee

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Published by Faculty of Dentistry, University of Toronto in [Toronto] .
Written in English


Book details:

Edition Notes

Thesis (Dip. Periodont.)--University of Toronto, 1985.

Statementby Jacinthe Larivee.
ID Numbers
Open LibraryOL14881026M

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One form of early-onset periodontal disease is known as localized juvenile periodontitis. Juvenile periodontitis typically may be first observed in individuals around puberty, ages 11 to The two forms of juvenile periodontitis are generalized and localized. The localized form has characteristic clinical features. Background: Studies have demonstrated that high levels of collagenase activity in gingival crevicular fluid (GCF) are associated with degradation of periodontal tissues in progressive periodontitis compared to periodontally healthy tissues. Because the activation of collagenases is an important issue in periodontitis, we have studied the activation of collagenase in gingival crevicular fluid Cited by:   effects on gingival fluid collagenase activity and attach- in periodontitis patients was investigated. 22 patients participated in this study, 11 with localized juvenile periodontitis (LJP. Neutrophil collagenase (matrix metalloproteinase 8 [MMP-8]) is an important mediator of tissue destruction in inflammatory diseases. Studies of anaerobic periodontal infections have shown that active MMP-8 in gingival crevicular fluid is associated with the degradation of periodontal tissues in progressive periodontitis whereas the latent enzyme is predominant in gingivitis.

S upernumerary teeth and localized juvenile periodontitis in the same patient is a very unusual finding. Only 5 cases are reported, 2 of which were identical twins. An additional 2 cases are presented in which localized juvenile periodontitis . Steven J. Challacombe, Penelope J. Shirlaw, in Mucosal Immunology (Third Edition), Juvenile periodontitis. Juvenile periodontitis is strongly associated with the bacterium Aa. In addition, it is accepted that antibodies to Aa have been found in all patients with juvenile periodontitis at levels significantly greater than the controls (Genco and Slots, ).   Early onset Periodontitis, Aggressive Periodontitis INTRODUCTION: Juvenile Periodontitis is the most uncommon severe form of the Periodontal disease Described by Wannenmacher() as destruction of the supporting tissues of the teeth that becomes clinically significant during adolescence or early adulthood. 5. Periodontal disease affects the mouths of the entire adult population to some degree and causes severe disease in 10 per cent. This is a concise account of the pathological processes involved in periodontal disease, its causes and progression, based on advances in contemporary research. Arational approach to treatment is presented on the basis of these processes.

The result is loosening of the teeth, and of course the risk of the infection taking more serious forms. Now Periodontitis generally affects people who are over 30 or 40 years of age. But certain forms of chronic periodontitis can actually affect young adults as well. And this form is called Juvenile Periodontitis. Analysis of gingival crevicular fluid in periodontitis, gingivitis, and controls revealed sixfold (P collagenase in periodontitis (n = 12) samples compared to. 1. J Periodontal Res. Sep;22(5) Collagenolytic activity in crevicular fluid from patients with chronic adult periodontitis, localized juvenile periodontitis and gingivitis, and from healthy control subjects.   Material and methods. The study group consisted of 55 adult subjects. They were classified according to their clinical diagnoses either as having generalized aggressive periodontitis (n = 27; 13 smokers and 14 non-smokers) or as periodontitis-free control group (n = 28; 14 smokers and 14 non-smokers).Total proteins, sIgA, peroxidase and collagenase .